Size :50ul
Clone Number:
Aliases:DKFZp762P2216 antibody; hTrabid antibody; Trabid antibody; TRAF-binding protein domain antibody; Ubiquitin thioesterase ZRANB1 antibody; Zinc finger Ran-binding domain-containing protein 1 antibody; ZRAN1_HUMAN antibody; ZRANB1 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:Q9UGI0
Immunogen:Recombinant Human Ubiquitin thioesterase ZRANB1 protein (111-397AA)
Raised in:Rabbit
Species Reactivity:Human
Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:200-1:500
Background:Specifically hydrolyzes \'Lys-29\'-linked and \'Lys-33\'-linked diubiquitin. Also cleaves \'Lys-63\'-linked chains, but with 40-fold less efficiency compared to \'Lys-29\'-linked ones. Positive regulator of the Wnt signaling pathway that deubiquitinates APC protein, a negative regulator of Wnt-mediated transcription. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration. May also modulate TNF-alpha signaling.
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjugate:Non-conjugated
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:ZRANB1
Research Areas:Epigenetics and Nuclear Signaling; Cell biology; Stem cells