ZFYVE19 antibody , Cat. # FNab09629

SKU: FNab09629

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Key regulator of abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Together with CHMP4C, required to retain abscission-competent VPS4(VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Deactivation of AURKB results in dephosphorylation of CHMP4C followed by its dissociation from ZFYVE19/ANCHR and VPS4 and subsequent abscission.

Immunogen:zinc finger, FYVE domain containing 19

Synonyms:FLJ14840, MPFYVE, ZFYVE19

Observed MW:52 kDa

Uniprot ID:Q96K21

Reactivity:Human

Tested Application:ELISA, WB, IHC

Recommended dilution:WB: 1:1000-1:10000; IHC: 1:20-1:200

Gene ID:84936

Research Area:Metabolism