YTHDC2 antibody , Cat. # FNab10487

SKU: FNab10487

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein binds to N6-methyladenosine, a common modified RNA nucleotide that is enriched in the stop codons and 3' UTRs of eukaryotic messenger RNAs. Binding of proteins to this modified nucleotide may regulate mRNA translation and stability. This gene may be associated with susceptibility to pancreatic cancer in human patients, and knockdown of this gene resulted in reduced proliferation in a human liver cancer cell line.

Immunogen:3'-5' RNA helicase YTHDC2

Synonyms:YTHDC2, CAHL

Observed MW:160 kDa

Uniprot ID:Q9H6S0

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IF

Recommended dilution:WB: 1:500-1:2000; IF: 1:50-1:200

Gene ID:

Research Area: