XRN2 antibody , Cat. # FNab09557

SKU: FNab09557

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Possesses 5'->3' exoribonuclease activity(By similarity). May promote the termination of transcription by RNA polymerase II. During transcription termination, cleavage at the polyadenylation site liberates a 5' fragment which is subsequently processed to form the mature mRNA and a 3' fragment which remains attached to the elongating polymerase. The processive degradation of this 3' fragment by this protein may promote termination of transcription. Binds to RNA polymerase II(RNAp II) transcription termination R-loops formed by G-rich pause sites(PubMed:21700224).

Immunogen:5'-3' exoribonuclease 2

Synonyms:XRN2, DHM1 like protein, DHP protein, 5' 3' exoribonuclease 2, 5 3 exoribonuclease 2

Observed MW:108 kDa

Uniprot ID:Q9H0D6

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB

Recommended dilution:WB: 1:200-1:1000

Gene ID:22803

Research Area:Metabolism, Developmental biology