XRCC4 Monoclonal Antibody(5C10)

SKU: BT-MCA0081

Size:100μL

Background:The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V(D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternative splicing generates several transcript variants.

Research_area:Epigenetics and nuclear signaling

Target_protein:XRCC4

applications:WB, IHC-p, IF, ICC, IP

Reactivity:Human

Clonality:Monoclonal

Clone ID:

Host:Mouse

Isotype:IgG

Gene Symbol/ Name:DNA repair protein XRCC4

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):38287

UniProt accession:Human: Q13426; Mouse: Q924T3

Synonyms:XRCC4; DNA repair protein XRCC4; X-ray repair cross-complementing protein 4

GeneID:Human: 7518; Mouse: 108138