XRCC4 Monoclonal Antibody

SKU: E-AB-22044

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Monoclonal Antibodies

Abbreviation: XRCC4

Target Synonym: DNA double strand break repair and V(D)J recombination protein XRCC4;DNA repair protein XRCC4;SSMED;X ray repair complementing defective repair in Chinese hamster cells 4;X ray repair cross complementing 4;X ray repair cross complementing protein 4;X-ray repair cross-complementing protein 4;XRCC 4;XRCC4;XRCC4

Research Areas: Cancer;Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Mouse

Species reactivity: Human

Application: WB;IHC-p;IF;IP

Isotype: IgG

Clonality: Monoclonal

Clone NO.: Clone:8K2

UNIProt ID: Q13426

Accession:

Background: Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.

Concentration: 1 mg/mL

Immunogen: Synthetic Peptide

Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Purification method: Protein A purification

Dilution: WB 1:500-1:2000;IHC 1:50-300;IF 1:50-1:200;IP 1:100-1:300

Calculated MW: 38kDa

ObservedMW: 38kDa