WISP2 Polyclonal Antibody

SKU: E-AB-53562

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:WISP2

Target Synonym:CCN family member 5;CCN5;Connective tissue growth factor like protein;Connective tissue growth factor related protein 58;Connective tissue growth factor-like protein;Connective tissue growth factor-related protein 58;CT58;CTGF L;CTGF-L;WISP 2;WISP-2;Wisp2;WISP2;Wnt 1 signaling pathway protein 2;WNT1 inducible signaling pathway protein 2;WNT1-inducible-signaling pathway protein 2

Research Areas:Cancer;Cardiovascular;Stem Cells

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:O76076

Accession:

Background:This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like (CT) domain. The encoded protein lacks the CT domain which is implicated in dimerization and heparin binding. It is 72% identical to the mouse protein at the amino acid level. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Its expression in colon tumors is reduced while the other two WISP members are overexpressed in colon tumors. It is expressed at high levels in bone tissue, and may play an important role in modulating bone turnover.

Concentration:0.8 mg/mL

Immunogen:Synthetic peptide of human WISP2

Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method:Antigen affinity purification

Dilution:IHC 1:30-1:150

Calculated MW:

ObservedMW: