WDFY2 Polyclonal Antibody

SKU: E-AB-18486

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: WDFY2

Target Synonym: PROF;Propeller-FYVE protein;RP11 147H23.1;WD repeat and FYVE domain containing 2;WD repeat and FYVE domain-containing protein 2;WD40 and FYVE domain containing 2;WD40- and FYVE domain-containing protein 2;WDF2;Wdfy2;WDFY2;ZFYVE22;Zinc finger FYVE domain-containing protein 22

Research Areas: Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q96P53

Accession:

Background: WD repeat and FYVE domain-containing protein 2 (WDFY2), also known as WDF2 and ZFYVE22, is a 400 amino acid protein that localizes to a set of small endosomes that are found within 100 nm from the plasma membrane. Highly conserved between species, WDFY2 consists of one FYVE-type zinc finger and seven WD repeats. The FYVE domain is a cysteine-rich domain of about 70 amino acids. Its primary role is to target signal-transducing proteins to cell membranes through binding to the membrane lipid phosphatidylinositol-3-phosphate with high specificity. WD-repeats are generally found in clusters of seven. They have no intrinsic catalytic activity, but they serve as a platform for protein-protein interactions. WDFY2 is suspected to play a critical role in the endocytic pathway.

Concentration: 0.6 mg/mL

Immunogen: Fusion protein of human WDFY2

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: WB 1:500-1:2000;IHC 1:30-1:150

Calculated MW: 45 kDa

ObservedMW: Refer to figures