VPS52 antibody , Cat. # FNab09447

SKU: FNab09447

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network(TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD(PubMed:15878329, PubMed:18367545). Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor(TFRC) to the plasma membrane(PubMed:25799061).

Immunogen:vacuolar protein sorting 52 homolog(S. cerevisiae)

Synonyms:ARE1, dJ1033B10.5, DKFZp547I194, RP5 1033B10, SAC2, SACM2L, VPS52

Observed MW:82 kDa

Uniprot ID:Q8N1B4

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IHC, IF, IP

Recommended dilution:WB: 1:200-1:2000?IP: 1:500-1:5000?IHC: 1:20-1:200; IF: 1:10-1:100

Gene ID:6293

Research Area:Signal Transduction