V-ATPase S1 rabbit pAb

SKU: ES8848

Size: 100μL

Source:Rabbit

Applications:WB;ELISA

Reactivity:Human;Mouse;Rat

Dilution:WB 1:500-2000, ELISA 1:10000-20000

Immunogen:Synthesized peptide derived from human V-ATPase S1. at AA range: 421-470

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):51kD

Human_gene_id:537

Human_swiss_prot_no:Q15904

Subcellular_location:Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Endoplasmic reticulum-Golgi intermediate compartment membrane . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Single-pass type I membrane protein . Cytoplasmic vesicle, clathrin-coated vesicle membrane ; Single-pass type I membrane protein . Not detected in trans-Golgi network. .

Other_name:V-type proton ATPase subunit S1 (V-ATPase subunit S1) (Protein XAP-3) (V-ATPase Ac45 subunit) (V-ATPase S1 accessory protein) (Vacuolar proton pump subunit S1)

Background:This gene encodes a component of a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site) and a transmembrane V0 domain. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. The encoded protein of this gene may assist in the V-ATPase-mediated acidification of neuroendocrine secretory granules. This protein may also play a role in early development. [provided by RefSeq, Aug 2013],