USP9X antibody , Cat. # FNab09344

SKU: FNab09344

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Deubiquitinase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Essential component of TGF-beta/BMP signaling cascade. Regulates chromosome alignment and segregation in mitosis by regulating the localization of BIRC5/survivin to mitotic centromeres. Specifically hydrolyzes both 'Lys-29'-and 'Lys-33'-linked polyubiquitins chains. Specifically deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Involved in axonal growth and neuronal cell migration.

Immunogen:ubiquitin specific peptidase 9, X-linked

Synonyms:Deubiquitinating enzyme FAF X, DFFRX, FAF, FAM, Fat facets in mammals, hFAM, Ubiquitin thiolesterase FAF X, USP9, USP9X

Observed MW:260-290 kDa

Uniprot ID:Q93008

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IF, IHC, IP

Recommended dilution:WB: 1:500-1:5000; IF: 1:10-1:100; IHC: 1?20-1?200; IP: 1?200-1?2000

Gene ID:8239

Research Area:Epigenetics, Cell Division and Proliferation, Metabolism, Developmental biology