USP2 Antibody - Cat. #: CSB-PA673833

SKU: CSB-PA673833

Size :50ul

Clone Number:

Aliases:41 kDa ubiquitin specific protease antibody; 41 kDa ubiquitin-specific protease antibody; Deubiquitinating enzyme 2 antibody; Ubiquitin carboxyl terminal hydrolase 2 antibody; Ubiquitin carboxyl-terminal hydrolase 2 antibody; ubiquitin specific peptidase 2 antibody; Ubiquitin specific processing protease 2 antibody; Ubiquitin specific protease 12 antibody; Ubiquitin specific protease 9 antibody; Ubiquitin specific protease, 41kD antibody; Ubiquitin thioesterase 2 antibody; Ubiquitin thiolesterase 2 antibody; Ubiquitin-specific-processing protease 2 antibody; Ubiquitin-specific-processing protease testis antibody; UBP-t antibody; UBP2_HUMAN antibody; UBP41 antibody; USP2 antibody; USP9 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O75604

Immunogen:Fusion protein of Human USP2

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:25-1:100

Background:This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:USP2

Research Areas:Epigenetics and Nuclear Signaling;Cell biology