ULA1 Polyclonal Antibody

SKU: BT-AP15352

Size:100μL

Background:The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.

Research_area:Cell biology; Epigenetics and nuclear signaling

Target_protein:NAE1

applications:WB, ELISA

Reactivity:Human, Rat, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:NEDD8-activating enzyme E1 regulatory subunit

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: Q13564; Mouse: Q8VBW6; Rat: Q9Z1A5

Synonyms:NEDD8-activating enzyme E1 regulatory subunit ;Amyloid beta precursor protein-binding protein 1, 59 kDa;APP-BP1;Amyloid protein-binding protein 1;Proto-oncogene protein 1

GeneID:Human: 8883