UCHL1/PGP9.5 antibody , Cat. # FNab09218

SKU: FNab09218

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:UCHL1(Ubiquitin carboxyl-terminal hydrolase isozyme L1) is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCHL1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. It is present in all neurons(PMID: 6343558). This protein is present in brain at concentrations at least 50 times greater than in other organs and is a major protein component of neuronal cytoplasm(PMID:7217993). And UCHL1 is a Parkinson's disease susceptibility gene(PMID:15048890).

Immunogen:ubiquitin carboxyl-terminal esterase L1(ubiquitin thiolesterase)

Synonyms:Neuron cytoplasmic protein 9.5, PARK5, PGP 9.5, PGP9.5, Ubiquitin thioesterase L1, Uch L1, UCHL1

Observed MW:26 kDa

Uniprot ID:P09936

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IHC, IP

Recommended dilution:WB: 1:500-1:5000; IHC?1:100-1:500; IP: 1:1000-1:5000

Gene ID:7345

Research Area:Neuroscience, Cancer, Metabolism, Epigenetics