UBE4A Polyclonal Antibody

SKU: BT-AP09367

Size:100μL

Background:UBE4A encodes a member of the U-box ubiquitin ligase family. The ubiquitination factor E4A is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn's disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Research_area:Epigenetics and Nuclear Signaling

Target_protein:UBE4A

applications:WB, IHC-p, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:UBE4A Antibody

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):122561

UniProt accession:Human: Q14139; Rat: Q6P7A2

Synonyms:UBE4A; KIAA0126; Ubiquitin conjugation factor E4 A

GeneID:Human: 9354; Rat: 315608