UBE2D2 Antibody - Cat. #: CSB-PA826958

SKU: CSB-PA826958

Size :100ul

Clone Number:

Aliases:E2(17)KB2 antibody; OTTHUMP00000223475 antibody; OTTHUMP00000223476 antibody; OTTHUMP00000223477 antibody; OTTHUMP00000223478 antibody; OTTHUMP00000224375 antibody; PUBC 1 antibody; PUBC1 antibody; UB2D2_HUMAN antibody; UBC 4 antibody; UBC 4/5 antibody; UBC4 antibody; UBC4/5 antibody; UBC4/5 homolog yeast antibody; UBCH 5B antibody; UBCH5B antibody; UBE2D2 antibody; Ubiquitin carrier protein antibody; Ubiquitin carrier protein D2 antibody; Ubiquitin conjugating enzyme E2 17 kDa 2 antibody; Ubiquitin conjugating enzyme E2 D2 antibody; Ubiquitin conjugating enzyme E2D 2 (homologous to yeast UBC4/5) antibody; Ubiquitin conjugating enzyme E2D 2 (UBC4/5 homolog yeast) antibody; Ubiquitin conjugating enzyme E2D 2 antibody; Ubiquitin protein ligase D2 antibody; Ubiquitin-conjugating enzyme E2 D2 antibody; Ubiquitin-conjugating enzyme E2(17)KB 2 antibody; Ubiquitin-conjugating enzyme E2-17 kDa 2 antibody; Ubiquitin-protein ligase D2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P62837

Immunogen:Synthesized peptide derived from C-terminal of Human UBE2D2.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6. Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria by DDX58/RIG-I in response to viral infection. Essential for viral activation of IRF3.

Jensen J.P., J. Biol. Chem. 270:30408-30414(1995).
Rolfe M., Proc. Natl. Acad. Sci. U.S.A. 92:3264-3268(1995).
Guinn B.-A., Biochem. Biophys. Res. Commun. 335:1293-1304(2005).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:UBE2D2

Research Areas:Epigenetics and Nuclear Signaling;Cell biology