TXNRD1 Monoclonal Antibody

SKU: AN200069P

Size::

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies

Abbreviation:TXNRD1

Target Synonym:TRXR;TXNRD;TXNRD1;GRIM-12;TR;TR1;TRXR1;TXNR;GRIM12;KDRF

Research Areas:Signal Transduction;Cell Biology;Metabolism

Conjugation:Unconjugated

Host:Mouse

Species reactivity:Human

Application:FCM;ICC/IF

Isotype:IgG1

Clonality:Monoclonal

Clone NO.:3G9

UNIProt ID:Q16881

Accession:

Background:This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 0' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms.

Concentration:1 mg/mL

Immunogen:Recombinant Human TXNRD1 protein

Buffer:0.2 μm filtered solution in PBS

Purification method:Protein A

Dilution:ICC/IF 1:20-1:100;FCM 1:25-1:100;

Calculated MW:

ObservedMW: