Trk C(Phospho Tyr516) Polyclonal Antibody

SKU: BT-AP08234

Size:100μL

Background:This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that| upon neurotrophin binding| phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas| secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene.

Research_area:Cancer; Neuroscience

Target_protein:NTRK3

applications:WB, IHC-p, IF, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:NT-3 growth factor receptor

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):94428

UniProt accession:Human: Q16288; Mouse: Q6VNS1; Rat: Q03351

Synonyms:NT-3 growth factor receptor; NTRK3; TRKC; NT-3 growth factor receptor; GP145-TrkC; Trk-C; Neurotrophic tyrosine kinase receptor type 3; TrkC tyrosine kinase

GeneID:Human: 4916; Mouse: 18213; Rat: 29613