Trk A(Phospho Tyr496) Polyclonal Antibody

SKU: BT-AP01748

Size:100μL

Background:This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that| upon neurotrophin binding| phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain| anhidrosis| self-mutilating behavior| mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found| but only three have been characterized to date.

Research_area:Neuroscience; Cancer; Metabolism

Target_protein:NTRK1

applications:WB, IF, ICC, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:High affinity nerve growth factor receptor

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):87497

UniProt accession:Human: P04629; Mouse: Q3UFB7; Rat: P35739

Synonyms:High affinity nerve growth factor receptor; NTRK1; MTC; TRK; TRKA; High affinity nerve growth factor receptor; Neurotrophic tyrosine kinase receptor type 1; TRK1-transforming tyrosine kinase protein; Tropomyosin-related kinase A; Tyrosine kinase receptor; Tyrosine kinase receptor A;

GeneID:Human: 4914; Mouse: 18211; Rat: 59109