TRIB2 Antibody - Cat. #: CSB-PA255282

SKU: CSB-PA255282

Size :50ul

Clone Number:

Aliases:C5FW antibody; FLJ57420 antibody; GS3955 antibody; Hypothetical protein TRB2 antibody; TRB-2 antibody; TRB2 antibody; TRIB 2 antibody; TRIB2 antibody; TRIB2_HUMAN antibody; Tribbles homolog 2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q92519

Immunogen:Full length fusion protein

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, IHC; ELISA:1:2000-1:10000, IHC:1:30-1:150

Background:This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:TRIB2

Research Areas:Cancer?Cardiovascular;Signal transduction?Stem cells