TPM3 antibody , Cat. # FNab08890

SKU: FNab08890

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.)

Background:This gene encodes a member of the tropomyosin family of actin-binding proteins. Tropomyosins are dimers of coiled-coil proteins that provide stability to actin filaments and regulate access of other actin-binding proteins. Mutations in this gene result in autosomal dominant nemaline myopathy and other muscle disorders. This locus is involved in translocations with other loci, including anaplastic lymphoma receptor tyrosine kinase (ALK) and neurotrophic tyrosine kinase receptor type 1 (NTRK1), which result in the formation of fusion proteins that act as oncogenes. There are numerous pseudogenes for this gene on different chromosomes. Alternative splicing results in multiple transcript variants.

Immunogen:tropomyosin 3

Synonyms:CAPM1, CFTD, HEL-189, HEL-S-82p, hscp30,NEM1, OK/SW-cl.5, TM-5,TM3, TM30, TM30nm, TM5, TPMsk3, TRK

Observed MW:37 kDa

Uniprot ID:P06753

Reactivity:Mouse

Tested Application:ELISA, WB, IHC

Recommended dilution:WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Gene ID:7170

Research Area:Neuroscience, Developmental biology