TNNI3 Polyclonal Antibody

SKU: E-AB-70275

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:TNNI3

Target Synonym:cardiac muscle;Cardiac troponin I;cardiomyopathy;dilated 2A (autosomal recessive);Cardiomyopathy;familial hypertrophic;7;included;CMD1FF;CMD2A;CMH7;cTnI;Familial hypertrophic cardiomyopathy 7;MGC116817;RCM1;Tn1;Tni;TNN I3;TNNC 1;TNNC1;TNNI3;TNNI3;Troponin I;Troponin I cardiac;Troponin I cardiac muscle;Troponin I cardiac muscle isoform;Troponin I type 3 cardiac;troponin I;cardiac 3;TroponinI;Ttroponin I type 3 (cardiac)

Research Areas:Cancer;Cardiovascular;Developmental Biology;Signal Transduction;Stem Cells

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P19429,P48787,P23693

Accession:

Background:Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).

Concentration:140 μg/mL

Immunogen:KLH conjugated Synthetic peptide corresponding to Mouse Cardiac Troponin I

Buffer:PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Purification method:Affinity purification

Dilution:WB 1:500-1:2000

Calculated MW:24kDa

ObservedMW:28kDa