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GeneBio Systems

TNFRSF11A Polyclonal Antibody

TNFRSF11A Polyclonal Antibody

SKU:E-AB-64599

Regular price $545.00 USD
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Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:TNFRSF11A

Target Synonym:TNFRSF11A;CD265;FEO;LOH18CR1;ODFR;OFE;OPTB7;OSTS;PDB2;RANK;TRANCER

Research Areas:Cancer;Cardiovascular;Immunology;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:IHC;IF

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:Q9Y6Q6

Accession:

Background:The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus.

Concentration:1mg/mL

Immunogen:Recombinant fusion protein of human TNFRSF11A (NP_003830.1).

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification method:Affinity purification

Dilution:IHC 1:50-1:100;IF 1:50-1:100

Calculated MW:

ObservedMW:

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