TNFAIP8 Antibody - Cat. #: CSB-PA993947

SKU: CSB-PA993947

Size :100ul

Clone Number:

Aliases:GG2 1 antibody; Head and neck tumor and metastasis-related protein antibody; MDC-3.13 antibody; NDED antibody; NF-kappa-B-inducible DED-containing protein antibody; SCC S2 antibody; SCC-S2 antibody; SCCS2 antibody; TFIP8_HUMAN antibody; TNF alpha-induced protein 8 antibody; TNF induced protein antibody; TNF-induced protein GG2-1 antibody; TNFAIP 8 antibody; TNFAIP8 antibody; Tumor necrosis factor alpha induced protein 8 antibody; Tumor necrosis factor alpha-induced protein 8 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O95379

Immunogen:Synthesized peptide derived from internal of Human TFIP8.

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IHC, IF; WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500

Background:Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.

Horrevoets A.J.G., Blood 93:3418-3431(1999).
Kumar D., J. Biol. Chem. 275:2973-2978(2000).
You Z., J. Biol. Chem. 276:26398-26404(2001).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:TNFAIP8

Research Areas:Cancer;Cell biology;Immunology;Signal transduction