TLR4 antibody , Cat. # FNab09837

SKU: FNab09837

Size:100ug

Purification:Protein A+G purification

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Mouse

Clonality:monoclonal

Clone ID:3E7

Isotype:IgG2b

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:TLR4, also named as CD284, belongs to the Toll-like receptor family. TLR4 cooperates with LY96 and CD14 to mediates the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.

Immunogen:toll-like receptor 4

Synonyms:ARMD10, CD284, hToll, TLR4, TOLL, toll like receptor 4

Observed MW:100 kDa

Uniprot ID:O00206

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IHC

Recommended dilution:WB: 1:1000-1:8000; IHC: 1:50-1:500

Gene ID:7099

Research Area:Neuroscience, Immunology, Signal Transduction, Developmental biology