tir Antibody, HRP conjugated - Cat. #: CSB-PA514896HB01EOF

SKU: CSB-PA514896HB01EOF

Size :50ug

Clone Number:

Aliases:tir antibody; espE antibody; ECSP_4676 antibody; Translocated intimin receptor Tir antibody; Secreted effector protein Tir antibody

Product Type:Polyclonal Antibody

Immunogen Species:Escherichia coli O157:H7 (strain TW14359 / EHEC)

UniProt ID:C6UYL8

Immunogen:Recombinant Escherichia coli O157:H7 Translocated intimin receptor Tir protein (252-362AA)

Raised in:Rabbit

Species Reactivity:Escherichia coli O157:H7

Tested Applications:ELISA

Background:Multifunctional protein that is required for efficient pedestal formation in host epithelial cells during infection. The extracellular region acts as a receptor for bacterial intimin, allowing the bacterium to attach tightly to the host-cell surface. Simultaneously, the intracellular region initiates a signaling cascade in the host cell, which leads to actin polymerization and formation of actin pedestals at the sites of bacterial adhesion (By similarity).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:HRP

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:tir

Research Areas:Others