TINF2 Antibody - Cat. #: CSB-PA874799LA01HU

SKU: CSB-PA874799LA01HU

Size :50ug

Clone Number:

Aliases:AW552114 antibody; D14Wsu146e antibody; DKCA3 antibody; MGC94711 antibody; TERF 1 (TRF 1) interacting nuclear factor 2 antibody; TERF 1 interacting nuclear factor 2 antibody; TERF1 (TRF1) interacting nuclear factor 2 antibody; TERF1 interacting nuclear factor 2 antibody; TERF1-interacting nuclear factor 2 antibody; Tin 2 antibody; TIN2 antibody; TINF 2 antibody; Tinf2 antibody; TINF2_HUMAN antibody; TRF 1 interacting nuclear factor 2 antibody; TRF1 interacting nuclear factor 2 antibody; TRF1-interacting nuclear protein 2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9BSI4

Immunogen:Recombinant Human TERF1-interacting nuclear factor 2 protein (210-451AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Plays a role in shelterin complex assembly. Isoform 1 may have additional role in tethering telomeres to the nuclear matrix.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:TINF2

Research Areas:Epigenetics and Nuclear Signaling