Timp1 Antibody, Biotin conjugated - Cat. #: CSB-PA16719D0Rb

SKU: CSB-PA16719D0Rb

Size :50ug

Clone Number:

Aliases:Timp1 antibody; Timp-1 antibody; Metalloproteinase inhibitor 1 antibody; Tissue inhibitor of metalloproteinases 1 antibody; TIMP-1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Rattus norvegicus (Rat)

UniProt ID:P30120

Immunogen:Recombinant Rat Metalloproteinase inhibitor 1 protein (24-217AA)

Raised in:Rabbit

Species Reactivity:Rat

Tested Applications:ELISA

Background:Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Also stimulates steroidogenesis by Leydig and ovarian granuloma cells; procathepsin L is required for maximal activity.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:Timp1

Research Areas:Cancer; Cardiovascular; Cell biology; Signal transduction