TEK Polyclonal Antibody

SKU: E-AB-12907

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:TEK

Target Synonym:Angiopoietin 1 receptor;Angiopoietin-1 receptor;CD202b;CD202b antigen;Endothelial tyrosine kinase;Endothelium specific receptor tyrosine kinase 2;hTIE 2;hTIE2;Hyk;p140 TEK;Soluble TIE2 variant 1;Soluble TIE2 variant 2;Tek;tek tyrosine kinase;TEK tyrosine kinase endothelial;tek tyrosine kinase;endothelial;TIE 2;TIE2;TIE2;Tunica interna endothelial cell kinase;Tyrosine kinase with Ig and EGF homology domains 2;Tyrosine kinase with Ig and EGF homology domains-2;Tyrosine protein kinase receptor TEK;Tyrosine protein kinase receptor TIE 2;Tyrosine-protein kinase receptor TEK;Tyrosine-protein kinase receptor TIE-2;Venous malformations multiple cutaneous and mucosal;VMCM 1;VMCM;VMCM1

Research Areas:Cancer;Cardiovascular;Developmental Biology;Signal Transduction;Stem Cells

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse

Application:IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:Q02763

Accession:

Background:The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smootHuman, Mouseuscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase.

Concentration:0.3 mg/mL

Immunogen:Synthetic peptide of human TEK

Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method:Affinity purification

Dilution:IHC 1:50-1:200

Calculated MW:

ObservedMW: