TCF7L1 Antibody - Cat. #: CSB-PA737037

SKU: CSB-PA737037

Size :100ul

Clone Number:

Aliases:bHLHb21 antibody; HMG box transcription factor 3 antibody; HMG box transcription factor antibody; OTTMUSP00000023419 antibody; T cell factor 3 antibody; TCF 3 antibody; TCF-3 antibody; TCF3 antibody; Tcf7l1 antibody; TF7L1_HUMAN antibody; Transcription factor 7 like 1 (T-cell specific, HMG-box) antibody; Transcription factor 7 like 1 antibody; Transcription factor 7-like 1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9HCS4

Immunogen:Synthesized peptide derived from internal of Human TCF7L1.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. Necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis By similarity. Down-regulates NQO1, leading to increased mitomycin c resistance.

Sagara N., Cancer Res. 60:5959-5962(2000).
Hillier L.W., Nature 434:724-731(2005).
Castrop J., Nucleic Acids Res. 20:611-611(1992).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:TCF7L1

Research Areas:Epigenetics and Nuclear Signaling;Stem cells