TBX1 Polyclonal Antibody

SKU: E-AB-53339

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:TBX1

Target Synonym:Brachyury;CAFS;CTHM;DGCR;DGS;DORV;T box;T box 1;T box 1 transcription factor;T box 1 transcription factor C;T box protein 1;T box transcription factor TBX 1;T box transcription factor TBX1;T-box protein 1;T-box transcription factor TBX1;TBX 1;TBX 1C;tbx1;TBX1;TBX1C;Testis specific T box protein;Testis-specific T-box protein;TGA;VCFS

Research Areas:Cancer;Epigenetics and Nuclear Signaling;Neuroscience

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:WB;IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:O43435

Accession:

Background:This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98% amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Concentration:0.7 mg/mL

Immunogen:Synthetic peptide of human TBX1

Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method:Antigen affinity purification

Dilution:WB 1:500-1:2000;IHC 1:25-1:100

Calculated MW:43 kDa

ObservedMW:Refer to figures