TBP Antibody - Cat. #: CSB-PA276652

SKU: CSB-PA276652

Size :100ul

Clone Number:

Aliases:GTF2D antibody; GTF2D1 antibody; HDL4 antibody; MGC117320 antibody; MGC126054 antibody; MGC126055 antibody; SCA17 antibody; TATA binding factor antibody; TATA box factor antibody; TATA sequence binding protein antibody; TATA sequence-binding protein antibody; TATA-binding factor antibody; TATA-box binding protein N-terminal domain antibody; TATA-box factor antibody; TATA-box-binding protein antibody; TBP antibody; TBP_HUMAN antibody; TFIID antibody; Transcription initiation factor TFIID TBP subunit antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P20226

Immunogen:Synthesized peptide derived from internal of Human TBP.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA.

Peterson M.G., Science 248:1625-1630(1990).
Mungall A.J., Nature 425:805-811(2003).
Gangloff Y.G., Mol. Cell. Biol. 21:5109-5121(2001).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:TBP

Research Areas:Isotype/Loading Controls;Epigenetics and Nuclear Signaling