TADA2L rabbit pAb

SKU: ES3551

Size: 100μL

Source:Rabbit

Applications:WB;ELISA

Reactivity:Human;Mouse;Rat;Monkey

Dilution:Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Immunogen:The antiserum was produced against synthesized peptide derived from human ADA2L. AA range:206-255

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):47kD

Human_gene_id:6871

Human_swiss_prot_no:O75478

Subcellular_location:Nucleus . Chromosome .

Other_name:TADA2A; TADA2L; KL04P; Transcriptional adapter 2-alpha; Transcriptional adapter 2-like; ADA2-like protein

Background:Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. Several alternatively spliced transcript variants encoding different isoforms of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Oct 2009],