Survivin(Phospho Thr117) Polyclonal Antibody

SKU: BT-AP14593

Size:100μL

Background:This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Research_area:Cancer; Cell biology; Neuroscience; Epigenetics and nuclear signaling

Target_protein:BIRC5

applications:IHC-p, IF, ICC, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Baculoviral IAP repeat-containing protein 5

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):16389

UniProt accession:Human: O15392; Mouse: O70201; Rat: Q9JHY7

Synonyms:Baculoviral IAP repeat-containing protein 5; BIRC5; API4; IAP4; Baculoviral IAP repeat-containing protein 5; Apoptosis inhibitor 4; Apoptosis inhibitor survivin

GeneID:Human: 332; Mouse: 11799; Rat: 64041