STEAP3 Antibody - Cat. #: CSB-PA235551

SKU: CSB-PA235551

Size :100ul

Clone Number:

Aliases:1010001D01Rik antibody; Dudlin 2 antibody; Dudlin2 antibody; Dudulin 2 antibody; Dudulin-2 antibody; Dudulin2 antibody; hpHyde antibody; hTSAP6 antibody; Metalloreductase STEAP3 antibody; MGC93147 antibody; pHyde antibody; Six transmembrane epithelial antigen of prostate 3 antibody; Six transmembrane prostate protein 3 antibody; Six-transmembrane epithelial antigen of prostate 3 antibody; STEA 3 antibody; STEA3_HUMAN antibody; STEAP 3 antibody; STEAP family member 3 antibody; STEAP family member 3 metalloreductase antibody; STEAP3 antibody; STMP 3 antibody; STMP3 antibody; TSAP 6 antibody; TSAP6 antibody; Tumor suppressor activated pathway protein 6 antibody; Tumor suppressor pHyde antibody; Tumor suppressor-activated pathway protein 6 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q658P3

Immunogen:Synthesized peptide derived from internal of Human STEA3.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB, IF; WB:1:500-1:3000, IF:1:100-1:500

Background:Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe3+ to Fe2+. Can also reduce of Cu2+ to Cu1+, suggesting that it participates in copper homeostasis. Uses NADP+ as acceptor. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.

Passer B.J., Proc. Natl. Acad. Sci. U.S.A. 100:2284-2289(2003).
Korkmaz C.G., Oncogene 24:4934-4945(2005).
Steiner M.S., Cancer Res. 60:4419-4425(2000).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:STEAP3

Research Areas:Metabolism;Signal transduction