ST18 rabbit pAb

SKU: ES3504

Size: 100μL

Source:Rabbit

Applications:WB;IHC;IF;ELISA

Reactivity:Human;Rat;Mouse;

Dilution:Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.

Immunogen:The antiserum was produced against synthesized peptide derived from human ZNF387. AA range:41-90

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):115kD

Human_gene_id:9705

Human_swiss_prot_no:O60284

Subcellular_location:Nucleus .

Other_name:ST18; KIAA0535; ZNF387; Suppression of tumorigenicity 18 protein; Zinc finger protein 387

Background:function:Repressor that binds to DNA sequences containing a bipartite element consisting of a direct repeat of the sequence 5'-AAAGTTT-3' separated by 2-9 nucleotides. Represses basal transcription activity from target promoters (By similarity). Inhibits colony formation in cultured breast cancer cells.,similarity:Contains 6 C2HC-type zinc fingers.,tissue specificity:Detected at low levels in heart, liver, kidney, skeletal muscel, pancreas, testis, ovary and prostate. Detected at even lower levels in mammary epithelial cells and breast cancer cells.,