SRGN Antibody - Cat. #: CSB-PA022664ESR1HU

SKU: CSB-PA022664ESR1HU

Size :50ul

Clone Number:

Aliases:Chondroitin sulfate proteoglycan core protein antibody; Cytolytic granule proteoglycan core protein antibody; FLJ12930 antibody; gp600 antibody; Hematopoetic proteoglycan core protein antibody; Mastocytoma proteoglycan core protein antibody; MGC9289 antibody; OTTHUMP00000019716 antibody; P.PG antibody; PG19 core protein antibody; Pgsg antibody; Platelet proteoglycan core protein antibody; platelet proteoglycan protein core antibody; PLATELET PROTEOGLYCAN PROTEIN CORE; PPG antibody; PPG antibody; PRG antibody; PRG1 antibody; PROTEOGLYCAN 1 antibody; proteoglycan 1; secretory granule antibody; Proteoglycan 10K core protein antibody; Proteoglycan peptide core protein antibody; PROTEOGLYCAN PROTEIN CORE FOR MAST CELL SECRETORY GRANULE antibody; secretory granule proteoglycan 1 antibody; Secretory granule proteoglycan core peptide antibody; Secretory granule proteoglycan core protein antibody; Serglycin antibody; serglycin proteoglycan antibody; Sgc antibody; Srgn antibody; SRGN_HUMAN antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P10124

Immunogen:Recombinant Human Serglycin protein (28-158AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:Plays a role in formation of mast cell secretory granules and mediates storage of various compounds in secretory vesicles. Required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T-lymphocytes. Plays a role in localizing neutrophil elastase in azurophil granules of neutrophils. Mediates processing of MMP2. Plays a role in cytotoxic cell granule-mediated apoptosis by forming a complex with granzyme B which is delivered to cells by perforin to induce apoptosis. Regulates the secretion of TNF-alpha and may also regulate protease secretion. Inhibits bone mineralization.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:SRGN

Research Areas:Cell biology; Metabolism; Signal transduction