SPTLC1 Antibody - Cat. #: CSB-PA022639ESR1HU

SKU: CSB-PA022639ESR1HU

Size :50ul

Clone Number:

Aliases:HSAN antibody; HSAN1 antibody; HSN1 antibody; LBC1 antibody; LCB 1 antibody; LCB1 antibody; Long chain base biosynthesis protein 1 antibody; MGC14645 antibody; Serine C palmitoyltransferase antibody; Serine palmitoyl CoA transferase 1 antibody; Serine palmitoyltransferase 1 antibody; Serine palmitoyltransferase long chain base subunit 1 antibody; Serine palmitoyltransferase subunit 1 antibody; Serine-palmitoyl-CoA transferase 1 antibody; SPT 1 antibody; SPT1 antibody; SPTC1_HUMAN antibody; SPTI antibody; SPTLC 1 antibody; SPTLC1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O15269

Immunogen:Recombinant Human Serine palmitoyltransferase 1 protein (37-310AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200

Background:Serine palmitoyltransferase (SPT). The heterodimer formed with SPTLC2 or SPTLC3 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC3-SPTSSA isozyme uses both C14-CoA and C16-CoA as substrates, with a slight preference for C14-CoA. The SPTLC1-SPTLC2-SPTSSB complex shows a strong preference for C18-CoA substrate, while the SPTLC1-SPTLC3-SPTSSB isozyme displays an ability to use a broader range of acyl-CoAs, without apparent preference.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:SPTLC1

Research Areas:Neuroscience; Cancer; Cardiovascular; Metabolism; Signal transduction