SOS1 antibody , Cat. # FNab08118

SKU: FNab08118

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Promotes the exchange of Ras-bound GDP by GTP(PubMed:8493579). Probably by promoting Ras activation, regulates phosphorylation of MAP kinase MAPK3 in response to EGF(PubMed:17339331). Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by promoting the Rac-specific guanine nucleotide exchange factor(GEF) activity(By similarity).

Immunogen:son of sevenless homolog 1

Synonyms:SOS1, GF1, GGF1, GINGF, HGF, NS4, son of sevenless homolog 1

Observed MW:180 kDa

Uniprot ID:Q07889

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IF

Recommended dilution:WB: 1:500 - 1:2000; IF: 1:50 - 1:100

Gene ID:6654

Research Area:cancer, Signal Transduction