SNX17 Antibody, Biotin conjugated - Cat. #: CSB-PA614877LD01HU

SKU: CSB-PA614877LD01HU

Size :50ug

Clone Number:

Aliases:Similar to a putative C elegans gene encoded in cosmid F17H10 antibody; Snx17 antibody; SNX17_HUMAN antibody; Sorting nexin 17 antibody; Sorting nexin-17 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q15036

Immunogen:Recombinant Human Sorting nexin-17 protein (280-457AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Critical regulator of endosomal recycling of numerous receptors, channels, and other transmembrane proteins. Binds to NPxY sequences in the cytoplasmic tails of target cargos. Plays a role in the sorting of endocytosed LRP1 and APP, and prevents their degradation. Required for maintenance of normal cell surface levels of APP and LRP1. Recycles internalized integrins ITGB1, ITGB5 and their associated alpha subunits, preventing them from lysosomal degradation. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:SNX17

Research Areas:Signal transduction