SMG7 Antibody - Cat. #: CSB-PA226815

SKU: CSB-PA226815

Size :100ul

Clone Number:

Aliases:breast cancer-associated antigen SGA-56M antibody; C1orf16 antibody; EST1 like protein C antibody; EST1 telomerase component homolog C antibody; EST1-like protein C antibody; EST1C antibody; ever shorter telomeres 1C antibody; FLJ23717 antibody; hSMG-7 antibody; nonsense mediated mRNA decay factor (C. elegans) antibody; Protein SMG7 antibody; SGA56M antibody; SMG 7 antibody; SMG-7 homolog antibody; Smg7 antibody; SMG7_HUMAN antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q92540

Immunogen:Synthesized peptide derived from internal of Human SMG7.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB, IF; WB:1:500-1:3000, IF:1:100-1:500

Background:Plays a role in nonsense-mediated mRNA decay. Recruits UPF1 to cytoplasmic mRNA decay bodies. Together with SMG5 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation.

Ohnishi T., Mol. Cell 12:1187-1200(2003).
Nagase T., DNA Res. 3:321-329(1996).
Nakajima D., DNA Res. 9:99-106(2002).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:SMG7

Research Areas:Epigenetics and Nuclear Signaling