SMAD5 Monoclonal Antibody

SKU: BT-MCA4231

Size:100μL

Background:Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD). SMAD5 is required for normal development of the cardiovascular system in vivo; lack of the SMAD5 gene results in apoptosis of cardiac myocytes. 3 Upregulation of SMAD5 has been reported to mediate apoptosis of gastric epithelial cells induced by Helicobacter pylori infection. Tissue specificity: Ubiquitous.

Research_area:Signal Transduction

Target_protein:SMAD5

applications:WB, IHC, ICC, FCM

Reactivity:Human, Rat

Clonality:Monoclonal

Clone ID:3H9

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:SMAD5

Immunogen:Purified recombinant fragment of human SMAD5 expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):52kDa

UniProt accession:Q99717

Synonyms:Dwfc, JV5-1, MADH5, DKFZp781C1895, DKFZp781O1323, SMAD5

GeneID:4090