SLC22A17 Antibody - Cat. #: CSB-PA910337

SKU: CSB-PA910337

Size :50ul

Clone Number:

Aliases:24p3 receptor antibody; 24p3R antibody; BOCT antibody; BOIT antibody; Brain type organic cation transporter antibody; Brain-type organic cation transporter antibody; hBOIT antibody; Lipocalin-2 receptor antibody; Neutrophil gelatinase associated lipocalin receptor antibody; Neutrophil gelatinase-associated lipocalin receptor antibody; NGAL receptor antibody; NgalR antibody; NGALR2 antibody; NGALR3 antibody; OTTHUMP00000082690 antibody; OTTHUMP00000082691 antibody; Potent brain type organic ion transporter antibody; S22AH_HUMAN antibody; Slc22a17 antibody; Solute carrier family 22 member 17 antibody; Solute carrier family 22 organic cation transporter member 17 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q8WUG5

Immunogen:Synthetic peptide of Human SLC22A17

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, IHC; ELISA:1:1000-1:5000, IHC:1:25-1:100

Background:Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:SLC22A17

Research Areas:Cancer;Metabolism;Signal transduction