SIR4 Polyclonal Antibody

SKU: BT-AP14232

Size:100μL

Background:This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.

Research_area:Cardiovascular; Cell biology; Epigenetics and nuclear signaling; Metabolism; Signal transduction

Target_protein:SIRT4

applications:WB, ELISA

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:NAD-dependent protein deacetylase sirtuin-4

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: Q9Y6E7; Mouse: Q8R216

Synonyms:NAD-dependent protein deacetylase sirtuin-4 ;EC 3.5.1.-;NAD-dependent ADP-ribosyltransferase sirtuin-4;EC 2.4.2.-;Regulatory protein SIR2 homolog 4;SIR2-like protein 4

GeneID:Human: 23409