SGK3 Antibody - Cat. #: CSB-PA839296ESR2HU

SKU: CSB-PA839296ESR2HU

Size :50ul

Clone Number:

Aliases:CISK antibody; Cytokine independent survival kinase antibody; DKFZp781N0293 antibody; Serine/threonine protein kinase Sgk3 antibody; Serine/threonine-protein kinase Sgk3 antibody; Serum/glucocorticoid regulated kinase 3 antibody; Serum/glucocorticoid regulated kinase family member 3 antibody; Serum/glucocorticoid regulated kinase like antibody; Serum/glucocorticoid-regulated kinase 3 antibody; Serum/glucocorticoid-regulated kinase-like antibody; SGK 2 antibody; SGK 3 antibody; SGK2 antibody; Sgk3 antibody; SGK3_HUMAN antibody; SGKL antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q96BR1

Immunogen:Recombinant Human Serine/threonine-protein kinase Sgk3 protein (1-150AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, proliferation, survival and migration. Up-regulates Na+ channels: SCNN1A/ENAC and SCN5A, K+ channels: KCNA3/KV1.3, KCNE1, KCNQ1 and KCNH2/HERG, epithelial Ca2+ channels: TRPV5 and TRPV6, chloride channel: BSND, creatine transporter: SLC6A8, Na+/dicarboxylate cotransporter: SLC13A2/NADC1, Na+-dependent phosphate cotransporter: SLC34A2/NAPI-2B, amino acid transporters: SLC1A5/ASCT2 and SLC6A19, glutamate transporters: SLC1A3/EAAT1, SLC1A6/EAAT4 and SLC1A7/EAAT5, glutamate receptors: GRIA1/GLUR1 and GRIK2/GLUR6, Na+/H+ exchanger: SLC9A3/NHE3, and the Na+/K+ ATPase. Plays a role in the regulation of renal tubular phosphate transport and bone density. Phosphorylates NEDD4L and GSK3B. Positively regulates ER transcription activity through phosphorylation of FLII. Negatively regulates the function of ITCH/AIP4 via its phosphorylation and thereby prevents CXCR4 from being efficiently sorted to lysosomes.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:SGK3

Research Areas:Metabolism; Signal transduction