SGK1(Phospho Ser422) Polyclonal Antibody

SKU: BT-AP07948

Size:100μL

Background:This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium| sodium| and chloride channels| suggesting an involvement in the regulation of processes such as cell survival| neuronal excitability| and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Research_area:Developmental biology; Signal transduction; Stem cells

Target_protein:SGK1

applications:WB, IHC-p, IF, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Serine/threonine-protein kinase Sgk1

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):48942

UniProt accession:Human: O00141; Mouse: Q9WVC6; Rat: Q06226

Synonyms:Serine/threonine-protein kinase Sgk1; SGK1; SGK; Serine/threonine-protein kinase Sgk1; Serum/glucocorticoid-regulated kinase 1

GeneID:Human: 6446; Mouse: 20393