SETB2 Polyclonal Antibody

SKU: BT-AP14142

Size:100μL

Background:This gene encodes a member of a family of proteins that contain a methyl-CpG-binding domain (MBD) and a SET domain and function as histone methyltransferases. This protein is recruited to heterochromatin and plays a role in the regulation of chromosome segregation. This region is commonly deleted in chronic lymphocytic leukemia. Naturally-occuring readthrough transcription occurs from this gene to the downstream PHF11 (PHD finger protein 11) gene. Alternative splicing results in multiple transcript variants.

Research_area:Epigenetics and nuclear signaling

Target_protein:SETDB2

applications:WB, ELISA

Reactivity:Human, Rat, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Histone-lysine N-methyltransferase SETDB2

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: Q96T68; Mouse: Q8C267

Synonyms:Histone-lysine N-methyltransferase SETDB2 ;EC 2.1.1.43;Chronic lymphocytic leukemia deletion region gene 8 protein;Lysine N-methyltransferase 1F;SET domain bifurcated 2

GeneID:Human: 83852