SERPIND1 Antibody - Cat. #: CSB-PA788694

SKU: CSB-PA788694

Size :100ul

Clone Number:

Aliases:D22S673 antibody; HC II antibody; HC-II antibody; HC2 antibody; HCF2 antibody; HEP2_HUMAN antibody; Heparin cofactor 2 antibody; Heparin cofactor II antibody; HLS2 antibody; Leuserpin 2 antibody; LS2 antibody; Protease inhibitor leuserpin 2 antibody; Protease inhibitor leuserpin-2 antibody; serine (or cysteine) proteinase inhibitor, clade D (heparin cofactor), member 1 antibody; Serpin D1 antibody; serpin peptidase inhibitor, clade D (heparin cofactor), member 1 antibody; SERPIND1 antibody; THPH10 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P05546

Immunogen:Synthesized peptide derived from internal of Human Heparin Cofactor II.

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, IHC, IF; IHC:1:50-1:100, IF:1:100-1:500

Background:Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III). Also inhibits chymotrypsin, but in a glycosaminoglycan-independent manner. Peptides at the N-terminal of HC-II have chemotactic activity for both monocytes and neutrophils.

Blinder M.A., Biochemistry 27:752-759(1988).
Herzog R., Biochemistry 30:1350-1357(1991).
Collins J.E., Genome Biol. 5:RESEARCH84.1-RESEARCH84.11(2004).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:SERPIND1

Research Areas:Cardiovascular