SERPINB5 Polyclonal Antibody

SKU: E-AB-14208

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: SERPINB5

Target Synonym: Maspin;Ovalbumin;Peptidase inhibitor 5;PI-5;PI5;protease inhibitor 5 (maspin);Protease inhibitor 5;Serine (or cysteine) peptidase inhibitor;clade B;member 5;serine (or cysteine) proteinase inhibitor;clade B (ovalbumin);member 5;Serpin B5;serpin family B member 5;Serpin peptidase inhibitor;Serpin peptidase inhibitor;clade B (ovalbumin);member 5;Serpinb5;SPB5;Spi5;Spi7

Research Areas: Cancer

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P36952

Accession:

Background: Maspin (mammary serine protease inhibitor) also known as serpin B5 is a protein that in humans is encoded by the SERPINB5 gene.[1] This protein belongs to the serpin (serine protease inhibitor) superfamily.[1] SERPINB5 also functions as a tumor suppressor gene in epithelial cells. The expressed protein suppresses the ability of cancer cells to invade and metastasize other tissues. The protein also functions as an angiogenesis inhibitor.It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.

Concentration: 0.5 mg/mL

Immunogen: Recombinant protein of human SERPINB5

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: WB 1:500-1:2000;IHC 1:100-1:300

Calculated MW: 42kDa

ObservedMW: