SCP2 Polyclonal Antibody

SKU: E-AB-52211

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: SCP2

Target Synonym: DKFZp686C12188;DKFZp686D11188;NLTP;NLTP;Non-specific lipid-transfer protein;Nonspecific lipid transfer protein;NSL TP;NSL-TP;OTTHUMP00000010488;OTTHUMP00000231766;OTTHUMP00000231767;OTTHUMP00000231768;OTTHUMP00000231769;OTTHUMP00000231770;OTTHUMP00000231772;OTTHUMP00000231773;OTTHUMP00000231774;OTTHUMP00000231776;OTTHUMP00000234662;Propanoyl CoA C acyltransferase;Propanoyl-CoA C-acyltransferase;SCP 2;SCP chi ;SCP X;SCP-2;SCP-chi;SCP-X;SCP2;SCPchi ;SCPX;Sterol carrier protein 2;Sterol carrier protein X

Research Areas: Cancer;Metabolism;Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P22307

Accession:

Background: This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.

Concentration: 0.6 mg/mL

Immunogen: Fusion protein of human SCP2

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: WB 1:500-1:2000;IHC 1:25-1:100

Calculated MW: 59 kDa

ObservedMW: Refer to figures